2,5-Difluoro-1,4-phenylenediboronic acid
(2,5-Difluoro-1,4-phenylene)diboronic acid
CAS: 1256358-83-4
Molecular Formula: C6H6B2F2O4
2,5-Difluoro-1,4-phenylenediboronic acid - Names and Identifiers
| Name | (2,5-Difluoro-1,4-phenylene)diboronic acid |
| Synonyms | 2,5-Difluoro-1,4-phenylenediboronic acid (4-borono-2,5-difluorophenyl)boronic acid (2,5-Difluoro-1,4-phenylene)diboronic acid Boronic acid, B,B'-(2,5-difluoro-1,4-phenylene)bis- |
| CAS | 1256358-83-4 |
2,5-Difluoro-1,4-phenylenediboronic acid - Physico-chemical Properties
| Molecular Formula | C6H6B2F2O4 |
| Molar Mass | 201.73 |
| Storage Condition | Inert atmosphere,2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD17015780 |
2,5-Difluoro-1,4-phenylenediboronic acid - Introduction
(2,5-Difluoro-1,4-phenyl) diboronic acid is an organic compound whose chemical formula is C6H4BF2O4. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
(2,5-Difluoro-1,4-phenyl) diboronic acid is a white to pale yellow solid, soluble in organic solvents such as dimethyl sulfoxide and ammonia. It has good stability and is not easily oxidized by air.
Use:
(2,5-Difluoro-1,4-phenyl) diboronic acid is an important intermediate in organic synthesis and is widely used in organic synthesis reactions. It is commonly used to participate in Suzuki coupling reactions to prepare various fluorine-containing organic compounds. In addition, it can also be used in the preparation of coordination compounds, fluorescent dyes and drugs.
Preparation Method:
A common method for the preparation of (2,5-Difluoro-1,4-phenyl) diboronic acid is obtained by the hydrogenation reaction of a borate ester. Specifically, 2,5-difluorophenylene and dimethyl borate are reacted in the presence of a base catalyst at an appropriate temperature and reaction time to produce (2,5-Difluoro-1,4-phenyl) diboronic acid.
Safety Information:
(2,5-Difluoro-1,4-phenyl) diboronic acid has no obvious danger under normal operating conditions. However, as a chemical, it is still necessary to pay attention to some conventional safety measures. When in use, wear appropriate personal protective equipment such as chemical protective gloves, glasses and laboratory coats. In addition, work in a well-ventilated environment and avoid inhalation or contact with skin. In case of accidental inhalation or contact with skin, rinse immediately with water and seek medical attention. When stored, should be sealed in a dry, cool place, avoid direct sunlight.
Nature:
(2,5-Difluoro-1,4-phenyl) diboronic acid is a white to pale yellow solid, soluble in organic solvents such as dimethyl sulfoxide and ammonia. It has good stability and is not easily oxidized by air.
Use:
(2,5-Difluoro-1,4-phenyl) diboronic acid is an important intermediate in organic synthesis and is widely used in organic synthesis reactions. It is commonly used to participate in Suzuki coupling reactions to prepare various fluorine-containing organic compounds. In addition, it can also be used in the preparation of coordination compounds, fluorescent dyes and drugs.
Preparation Method:
A common method for the preparation of (2,5-Difluoro-1,4-phenyl) diboronic acid is obtained by the hydrogenation reaction of a borate ester. Specifically, 2,5-difluorophenylene and dimethyl borate are reacted in the presence of a base catalyst at an appropriate temperature and reaction time to produce (2,5-Difluoro-1,4-phenyl) diboronic acid.
Safety Information:
(2,5-Difluoro-1,4-phenyl) diboronic acid has no obvious danger under normal operating conditions. However, as a chemical, it is still necessary to pay attention to some conventional safety measures. When in use, wear appropriate personal protective equipment such as chemical protective gloves, glasses and laboratory coats. In addition, work in a well-ventilated environment and avoid inhalation or contact with skin. In case of accidental inhalation or contact with skin, rinse immediately with water and seek medical attention. When stored, should be sealed in a dry, cool place, avoid direct sunlight.
Last Update：2024-04-09 20:52:54
